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KMID : 0376219840210040969
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Chonnam Medical Journal
1984 Volume.21 No. 4 p.969 ~ p.978
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Mass/Volume Ratio of the Left Ventricle in Essential Hypertension
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李昌洙/Lee, Chang Soo
尹永?/丁明鎬/朴玉圭/Yoon, Young Geun/Jeong, Myung Ho/Park, Ock Kyu
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Abstract
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In order to observe the patterns of anatomic changes of the left ventricle (LV) in hypertensive subjects, 70 patients with essential hypertension of varying severity and of the different states of compensation, were examined by means of M-mode echocardiography. The mass to volume ratio(MVR) of the left ventricle and the parameters representing left ventricular wall geometry, peak systolic stress and performances were measured in each group of the patients divided in reference to the severity of the hypertension, the pattern of the hypertrophy of the left ventricular wall and the state of the compensations, and those of each group were compared.
The results of the study were as follows:
1. The MVR was increased in hypertensive subjects, the more in the groups with the increasing severity of hypertension and in the group with increased mussle mass and in the group with left ventricvlar decompensation.
2. The MVR was increased with highly significant positive correlation with the relative wall thickness of the LV and LV mass index(r=0.91, r=0.69, P<0.001, respectively), but weakly correlated with systolic and diastolic blood pressure(r=0.48, r=0.49, P<0.001, repectively), whereas it was decreased in relation with the increasing peak systolic wall stress, stroke volume index or cardiac index(r=-0.57, r=-0.30, r=-0.20, respectively). Ejection fraction, mean velosity of the circumferencial fiber shortening and the end-diastolic volume index appeared to have no specific correlation with the MVR.
3. The peak systolic wall stress(PS) of the hypertensive patient was not different from that of control. But the patient whose interventricular septal thickness was less than 1.2cm manifested increased PS(P4. Left ventricluar mass index, relative wall thickness and diastolic volume index were significantly increased in the hypertensive subjects, more prominently in those patients with decompensated left ventricle(P<0.001).
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